Phytochemical Screening and Toxicity Assessment of <>Imperata cylindrica</i> (L.) P. Beauv. (Poaceae) Raw Extracts with Brine Shrimp (<i>Artemia salina</i>) Lethality Assay

Background: Herbal medicinal preparations are used as dietary supplements for disease prevention and alternative/complementary medicine. The growing interest in herbal medicine raises the question of its safety efficacy. Numerous recorded cases intoxication toxicological studies reveal that plants can be toxic, which hinders their safe use. Plant intoxications related to a variety factors include plant organs many extraction solvents. Little data on is available. need investigate important Imperata cylindrica, poaceae, one few Materials & Methods: To expand data, water, 70% ethanol, 30% acetone extracts leaves roots, obtained by maceration reflux methods, were phytochemicals molecules qualitative detection toxicity test brine shrimp lethality assay. Results: analysis different revealed presence alkaloids, polyphenolic compounds, saponins, polyterpenoids. endpoint was lethal concentration 50 (LC50). leaves’ LC50 between 489.78 μg/mL 1066.6 μg/mL. As root extracts, 341.98 1530 Discussion: compounds’ justifies use cylindrica plant. According Clarkson classification moderately toxic (LC50: 168.47 μg/mL), leaf weakly 527.25 μg/mL). extrapolation made relation Gosselin, Smith, Hodge scale, allows us characterize non-toxic humans oral route. Conclusion: This result base more precise studies.